Abstract Introduction Myopia and its vision-threatening complications present a significant public health problem.This review aims to provide an updated overview of the multitude of known and emerging interventions to control myopia, including their potential effect, safety, and costs.Methods A systematic literature search of three databases was co
Background: The full potential of social entrepreneurship remains challenging to achieve, despite continuous efforts in various economies, including South-East Gloves Asia.Several obstacles need to be addressed, such as the scarcity of skilled employees, limited business understanding among founders, difficulties accessing funding and infrastructur
Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces ectopic L-2HG accumulation, resulting in ne
Vitamin D deficiency is a global health concern that is estimated to afflict over one billion people globally.The major role of vitamin D is that of a regulator of calcium and phosphate metabolism, thus, being essential for proper bone mineralisation.Concomitantly, vitamin D is known to exert numerous extra-skeletal actions.For example, it has beco
Carnosine is an endogenous dipeptide composed of β-alanine and L-histidine.This naturally occurring molecule is present at high concentrations in several mammalian excitable tissues such as muscles and brain, while it can be found at low concentrations in a few invertebrates.Carnosine has been shown to be involved in different cellular defense